Generalizability of Randomized Trial Results to Target Populations
نویسندگان
چکیده
منابع مشابه
Generalizability of anaesthesia study populations.
In this issue of the British Journal of Anaesthesia, Sury and colleagues present extensive audit data derived from a survey of anaesthetic departments in the UK, with the general aim of characterizing current National Health Service (NHS) anaesthetic activity. A more specific aim was to provide a context for the release of the upcoming 5th National Audit Project (NAP5) in which the incidence an...
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The gold standard for assessing treatment effects is the randomized clinical trial. Providers are fortunate to have a robust set of trials with .80 000 participants showing important benefits and reassuring safety of the non-vitamin K oral anticoagulants (NOACs) relative to warfarin for stroke prevention in atrial fibrillation (AF). 4 Based on the consistent findings of these trials, providers ...
متن کاملThe use of propensity scores to assess the generalizability of results from randomized trials.
Randomized trials remain the most accepted design for estimating the effects of interventions, but they do not necessarily answer a question of primary interest: Will the program be effective in a target population in which it may be implemented? In other words, are the results generalizable? There has been very little statistical research on how to assess the generalizability, or "external val...
متن کاملInvestigating generalizability of results from a randomized controlled trial of the management of chronic widespread pain: the MUSICIAN study
The generalisability of randomised controlled trials will be compromised if markers of treatment outcome also affect trial recruitment. In a large trial of chronic widespread pain, we aimed to determine the extent to which randomised participants represented eligible patients, and whether factors predicting randomisation also influenced trial outcome. Adults from 8 UK general practices were sur...
متن کاملGeneralizability of trial results to elderly Medicare patients with advanced solid tumors (Alliance 70802).
BACKGROUND In the United States, patients who enroll in chemotherapy trials seldom reflect the attributes of the general population with cancer, as they are often younger, more functional, and have less comorbidity. We compared survival following three chemotherapy regimens according to the setting in which care was delivered (ie, clinical trial vs usual care) to determine the generalizability ...
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ژورنال
عنوان ژورنال: Research on Social Work Practice
سال: 2017
ISSN: 1049-7315,1552-7581
DOI: 10.1177/1049731517720730